FUSION PROTEIN COMPRISING ANTI-C-MET ANTIBODY AND VEGF BINDING FRAGMENT

摘要

Provided are a fusion protein with anti-c-Met antibodies and VEGF binding fragments; double target antibodies including the fusion protein; polynucleotide which encodes the fusion protein; transformants including the polynucleotide; a pharmaceutical composition including the double target antibodies as an active ingredient; and a method for manufacturing the double target antibodies which target both c-Met and VEGF with improved anticancer and inhibitory effect of new blood vessel, wherein the method comprises a step of connecting anti-c-Met antibodies with VEGF binding fragments.