| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: group of inventions relates to medicine and deals with a pharmaceutical composition for stimulation of growth and reproduction of cells in humans and other animals, which contains suitable pharmaceutical fillers and contains polyethyleneglycol-containing conjugate of the human growth hormone prodrug. The group of inventions also relates to a method of obtaining the said conjugate.EFFECT: group of inventions provides longer activity of rhGH in comparison with non-modified rhGH, which makes it possible to reduce a dose and a mode of introduction, and reduce a level of lipoatrophy.13 cl, 27 ex, 11 dwg, 2 tbl |
