发明名称 METHOD OF FINAL DIFFERENTIATION INDUCTION
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: claimed is a pharmaceutical composition for peroral introduction for treatment of malignant tumours in a patient, excluding non-Hodgkin's lymphoma, myelodysplastic syndrome, leukemia and malignant tumours with leukocyte infiltration, which contains up to 400 mg of the solid drug form of suberoylanilide hydroxamic acid (SAHA), or its pharmaceutically acceptable salt, or a hydrate.EFFECT: solid drug form of SAHA, which has a crystalline structure was characterised by stability and provided partial reaction of a malignant tumour of the larynx with metastases or shrinkage of the solid tumour by results of CT-scanning.22 cl, 12 dwg, 7 tbl
申请公布号 RU2530648(C2) 申请公布日期 2014.10.10
申请号 RU20100108448 申请日期 2010.03.09
申请人 MERK EHJCHDIEHJSI RISERCH, LLS;SLOAN-KETTERING INSTIT'JUT FOR KEHNSER RISERCH 发明人 RICHON VIKTORIJA M.;CHAO KH. DZHUDI;MILLER TOMAS A.;KELLI V. KEVIN
分类号 A61K9/48;A61K31/16;A61K31/13;A61K31/165;A61K31/19;A61K31/426;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/445;A61K31/4706;A61K31/4709;A61K38/12;A61K47/12;A61K47/38;A61P35/00;A61P43/00;C07C259/04;G01N33/579 主分类号 A61K9/48
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