| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: group of inventions relates to biotechnology. Claimed is a method of enriching probiotic microorganisms, selected from yeasts and bacteria, with organic selenium. A microorganism is cultivated in a medium, containing a compound of general formulaor its salt, a stereoisomer or a mixture of stereoisomers in any ratio or its ether derivative. Also claimed are probiotic bacteria, enriched with organic selenium, with the content of organic selenium more than 50 mcgSe/g by dry weight, with the content of selenomethionine constituting more than 50% of the total content of selenium in the bacterium. Also claimed is application of enriched by the said way probiotic bacteria in a cosmetic, pharmaceutical or food product.EFFECT: invention provides enrichment of probiotic microorganisms with non-toxic organic selenium with an increased output.12 cl, 6 dwg, 4 tbl, 4 ex |
