发明名称 CHIRAL DIACYLHYDRAZINE LIGANDS FOR MODULATING EXPRESSION OF EXOGENOUS GENES VIA ECDYSONE RECEPTOR COMPLEX
摘要 PROBLEM TO BE SOLVED: To provide diacylhydrazine ligands and chiral diacylhydrazine ligands for use with ecdysone receptor-based inducible gene expression system useful for modulating expression of a target gene of interest in a host cell.SOLUTION: This invention relates to a compound expressed by a formula 1, or pharmaceutically acceptable salts, hydrates, crystalline forms or amorphous forms thereof, wherein: A is alkoxy or the like; B is aryl or the like; and Rand Rare each alkyl or the like.
申请公布号 JP2014193875(A) 申请公布日期 2014.10.09
申请号 JP20140095224 申请日期 2014.05.02
申请人 INTREXON CORP 发明人 ROBERT E HORMANN;LI BING
分类号 C07C243/38;A61K31/166;A61K31/341;A61K31/357;A61K31/36;A61K31/381;A61K31/44;A61P43/00;C07D213/82;C07D307/68;C07D317/68;C07D319/18;C07D333/38;C12N15/09 主分类号 C07C243/38
代理机构 代理人
主权项
地址