发明名称 HEXADECYLOXYPROPYL CIDOFOVIR FOR THE TREATMENT OF DOUBLE-STRANDED DNA VIRUS INFECTION
摘要 The present application provides methods and compositions for treatment or prevention of dsDNA virus infection in post-hematopoietic cell transplant (HCT or HSCT) patients.
申请公布号 US2014303092(A1) 申请公布日期 2014.10.09
申请号 US201214354481 申请日期 2012.10.26
申请人 CHIMERIX, INC. 发明人 Painter George R.;Lanier Ernest Randall;Almond Merrick R.;Margolskee Dorothy;Painter Gwendolyn Powell
分类号 C07F9/6512;A61K45/06;A61K31/675 主分类号 C07F9/6512
代理机构 代理人
主权项 1. A method of treatment, prevention, or delaying on-set of cytomegalovirus (CMV) infection or a CMV infection associated disease or disorder, the method comprising orally administering to a subject a pharmaceutical composition comprising a therapeutically effective dose of a compound selected from: and a pharmaceutically acceptable salt thereof, wherein said subject is a post-hematopoietic stem cell transplant (HSCT) subject and is CMV seropositive before transplantation.
地址 Durham NC US