发明名称 ANTI-C-MET/ANTI-EGFR BISPECIFIC ANTIBODIES
摘要 There are provided an anti-c-Met/anti-EGFR bispecific antibody, a method for preventing and/or treating cancer using the same, and an anti-EGFR scFv fragment.
申请公布号 US2014302029(A1) 申请公布日期 2014.10.09
申请号 US201414231376 申请日期 2014.03.31
申请人 Samsung Electronics Co., Ltd. 发明人 CHO MI YOUNG;LEE SEUNG HYUN;CHEONG KWANG HO;LIN POWEI;HWANG JAE WOONG;YI CHRISTINA;KOH YOUNG JUN
分类号 C07K16/32 主分类号 C07K16/32
代理机构 代理人
主权项 1. An anti-c-Met/anti-EGFR bispecific antibody comprising (a) an anti-c-Met antibody or an antigen-binding fragment thereof and (b) an anti-EGFR antibody or an antigen-binding fragment thereof, wherein the anti-c-Met antibody or the antigen-binding fragment thereof specifically binds to an epitope comprising 5 or more contiguous amino acids within the SEMA domain of c-Met protein (SEQ ID NO: 79).
地址 Suwon-si KR