发明名称 |
ANTI-C-MET/ANTI-EGFR BISPECIFIC ANTIBODIES |
摘要 |
There are provided an anti-c-Met/anti-EGFR bispecific antibody, a method for preventing and/or treating cancer using the same, and an anti-EGFR scFv fragment. |
申请公布号 |
US2014302029(A1) |
申请公布日期 |
2014.10.09 |
申请号 |
US201414231376 |
申请日期 |
2014.03.31 |
申请人 |
Samsung Electronics Co., Ltd. |
发明人 |
CHO MI YOUNG;LEE SEUNG HYUN;CHEONG KWANG HO;LIN POWEI;HWANG JAE WOONG;YI CHRISTINA;KOH YOUNG JUN |
分类号 |
C07K16/32 |
主分类号 |
C07K16/32 |
代理机构 |
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代理人 |
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主权项 |
1. An anti-c-Met/anti-EGFR bispecific antibody comprising (a) an anti-c-Met antibody or an antigen-binding fragment thereof and (b) an anti-EGFR antibody or an antigen-binding fragment thereof,
wherein the anti-c-Met antibody or the antigen-binding fragment thereof specifically binds to an epitope comprising 5 or more contiguous amino acids within the SEMA domain of c-Met protein (SEQ ID NO: 79). |
地址 |
Suwon-si KR |