MARKERS OF ACUTE KIDNEY FAILURE

摘要

The present invention relates to a method of determining the risk of acute kidney injury comprising determining the amount of a marker selected from VCAN, NRP1, CCL2, CCL19, COL3A1, GZMM or any combination thereof in a sample.

主权项

1. A method of determining the risk for acute kidney injury disease in a patient comprising the steps of:
measuring a concentration of at least one kidney risk factor (KRF) in a sample from said patient; comparing the measured KRF concentration to a control value; and determining the patient's risk of acute kidney injury based on comparing the measured KRF concentration to the control value, wherein the at least one KRF is a predictor of disease progression and is selected from the group consisting of VCAN, NRP1, CCL2, CCL19, COL3A1 and GZMM, and wherein the patient is suffering from a chronic disease selected from the group consisting of diabetes, hypertension, and heart disease.