| 摘要 |
A sLASER-first-COSY sequence is disclosed. After a delay time, &Dgr;1, from application of a first 90° radio frequency (RF) pulse, a first pair of adiabatic full-passage (AFP) pulses are applied to an object in a MRI scanner. The first 90° RF pulse is a non- adiabatic slice-selective 90° RF pulse and the first pair of AFP pulses is separated by an inter-pulse time interval, &Dgr;2. A second pair of AFP pulses, separated by the time &Dgr;2, is then applied, followed by a second 90° RF pulse. The second 90° RF pulse is a non-adiabatic non-slice-selective 90° RF pulse, MR signal is acquired after an echo time (TE) from application of the excitation RF pulse. The present method may achieve intended full magnetization transfer between a coupled spin pair of a metabolite and maintain metabolite cross peak intensity of a coupled spin pair of a metabolite in the object. |
