发明名称 FOXM1 PEPTIDE AND MEDICINAL AGENT COMPRISING THE SAME
摘要 <p>PROBLEM TO BE SOLVED: To provide means which enables a cancer immunotherapy for about 30% of various types of cancer patients in Japan who express forkhead box M1 (FOXM1) at high levels, by identifying a FOXM1-derived from peptide which can bind to HLA-A2 to activate a human killer T-cell that can injure a cancer cell.SOLUTION: Disclosed is a peptide showing inducing activity of killer T cells, in which one, two or several amino acids are substituted, deleted, inserted and/or added in a peptide consisting of a specific amino acid sequence or the peptide.</p>
申请公布号 JP2014193893(A) 申请公布日期 2014.10.09
申请号 JP20140103000 申请日期 2014.05.19
申请人 ONCOTHERAPY SCIENCE LTD 发明人 NISHIMURA TAIJI;YOKOMINE KAZUNORI;TSUNODA TAKUYA;NAKAMURA YUSUKE
分类号 C07K7/06;A61K39/00;A61P35/00;C07K14/82;C07K16/32;C12N5/0781;C12N5/0783;C12N5/0784;C12N5/0786;C12N15/09 主分类号 C07K7/06
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