MASKLESS IMAGING OF DENSE SAMPLES USING MULTI-HEIGHT LENSFREE MICROSCOPE

摘要

A method of imaging includes illuminating a sample spaced apart from an image sensor at a multiple distances. Image frames of the sample obtained at each distance are registered to one another and lost phase information from the registered higher resolution image frames is iteratively recovered. Amplitude and/or phase images of the sample are reconstructed based at least in part on the recovered lost phase information.

主权项

1. A method of imaging a sample comprising:
illuminating a sample spaced apart from an image sensor at a first distance with an illumination source; obtaining an image of the sample from an image sensor with the sample spaced apart from the image sensor at the first distance; illuminating the sample spaced apart from an image sensor at a one or more distances different from the first distance with an illumination source; obtaining an image of the sample from an image sensor with the sample spaced apart from the image sensor at the one or more distances different from the first distance; registering the images of the sample obtained at the one or more distances and the image of the sample obtained at the first distance; recovering lost phase information from the registered images; and reconstructing an amplitude or phase image of the sample based at least in part on the recovered lost phase information.