| 发明名称 |
COMPOSITIONS AND METHODS FOR IN VIVO EXCISION OF HIV-1 PROVIRAL DNA |
| 摘要 |
Methods and kits for excising HIV-1 DNA in vivo are provided, which employ Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-Associated (cas) proteins. Vectors harboring nucleic acids encoding one or more guide RNA, wherein said guide RNA hybridizes with a target HIV-1 DNA are also provided. |
| 申请公布号 |
WO2014165349(A1) |
申请公布日期 |
2014.10.09 |
| 申请号 |
WO2014US31674 |
申请日期 |
2014.03.25 |
| 申请人 |
TRUSTEES OF DARTMOUTH COLLEGE |
发明人 |
HOWELL, ALEXANDER, L.;ESZTERHAS, SUSAN, K. |
| 分类号 |
C12N15/11 |
主分类号 |
C12N15/11 |
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