发明名称 DIAMINOPYRIMIDINE AS P2X3 AND P2X2/3 ANTAGONIST
摘要 PROBLEM TO BE SOLVED: To provide a compound and method for treating a disease mediated by P2Xand/or P2Xreceptor antagonists.SOLUTION: A compound is represented by the formula (I). In the formula, D is optionally oxygen, X is -CH2-; -O-; or the like, Y is hydrogen; or -N, R, R, R, R, R, R, Rand Rare selected from hydrogen; alkyl; alkenyl; cycloalkyl; cycloalkenyl; halo; haloalkyl; hydroxyalkyl; or the like.
申请公布号 JP2014193906(A) 申请公布日期 2014.10.09
申请号 JP20140115301 申请日期 2014.06.03
申请人 F. HOFFMANN-LA ROCHE AG 发明人 CARTER DAVID SCOTT;DILLON MICHAEL PATRICK;HAWLEY RONALD CHARLES;LIN CLARA JEOU JEN;PARISH DANIEL WARREN;BROKA CHRIS ALLEN;JAHANGIR ALAM
分类号 C07D239/48;A61K31/505;A61K31/506;A61K31/538;A61P1/04;A61P9/10;A61P13/02;A61P13/08;A61P13/10;A61P25/04;A61P25/06;A61P31/04;A61P31/12;A61P33/00;A61P39/02;A61P43/00;C07D239/49;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12 主分类号 C07D239/48
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