| 发明名称 |
Use of EDG Receptor Binding Agents in Cancer |
| 摘要 |
Provided is a method for treating solid tumors, e.g tumor invasiveness, and particularly inhibiting or controlling deregulated angiogenesis, using a sphingosine-1-phosphate receptor agonist, optionally in combination with a chemotherapeutic agent. The invention also comprises a combination of a sphingosine-1-phosphate receptor agonist with a chemotherapeutic agent. |
| 申请公布号 |
US2014303257(A1) |
申请公布日期 |
2014.10.09 |
| 申请号 |
US201414311838 |
申请日期 |
2014.06.23 |
| 申请人 |
Baumruker Thomas;Brinkmann Volker;La Montagne Kenneth Richard;Lassota Peter T.;Mechtcheriakova Diane;Wood Jeanette Majorie |
发明人 |
Baumruker Thomas;Brinkmann Volker;La Montagne Kenneth Richard;Lassota Peter T.;Mechtcheriakova Diane;Wood Jeanette Majorie |
| 分类号 |
A61K31/137 |
主分类号 |
A61K31/137 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method for inhibiting or controlling deregulated angiogenesis, e.g. sphingosine-1-phosphate (S1P) mediated angiogenesis, in a subject in need thereof, comprising administering to said subject a therapeutically effective amount of a S1P receptor agonist. |
| 地址 |
Moedling AT |
