| 发明名称 |
TARGETING AN AMPHIREGULIN-DERIVED CELL SURFACE NEO-EPITOPE |
| 摘要 |
Antibodies to an amphiregulin neo-epitope, fragments thereof, and compositions comprising such are provided. Therapies for cancers in which cells thereof express amphiregulin are provided, as well as assays for identifying additional agents useful in such therapies. |
| 申请公布号 |
US2014302050(A1) |
申请公布日期 |
2014.10.09 |
| 申请号 |
US201214356724 |
申请日期 |
2012.10.24 |
| 申请人 |
ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY |
发明人 |
Kenny Paraic Anthony;Najarro Kelly Susan Levano;Jung Eric Hoonee |
| 分类号 |
C07K16/22;A61K35/14 |
主分类号 |
C07K16/22 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated antibody, or an isolated fragment of an antibody, or an aptamer, which binds to a membrane-associated extracellular portion of a cleaved amphiregulin precursor protein. |
| 地址 |
Bronx NY US |
