发明名称 |
Devices and methods for preventing platelet activation |
摘要 |
<p>Methods for inhibiting a biomaterial-associated thrombotic event comprise reducing the number of platelets that bind to the biomaterial, or inhibiting platelet activation, by attaching CD47 or the Ig domain thereof to the surface of the biomaterial. Methods of the present invention inhibit thrombi formation on or near a biomaterial that is on the surface of an implant, medical device, tube, or therapeutic delivery vehicle. Also provided are kits for practicing these methods and the modified biomaterials.</p> |
申请公布号 |
AU2013235393(A1) |
申请公布日期 |
2014.10.09 |
申请号 |
AU20130235393 |
申请日期 |
2013.03.15 |
申请人 |
THE CHILDREN'S HOSPITAL OF PHILADELPHIA |
发明人 |
STACHELEK, STANLEY J.;FINLEY, MATTHEW J.;LEVY, ROBERT J. |
分类号 |
C07K14/745;A61F2/00;A61K38/36;A61P7/02 |
主分类号 |
C07K14/745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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