METHODS FOR TREATING VASCULAR LEAK SYNDROME

摘要

PROBLEM TO BE SOLVED: To provide methods of preventing vascular leakage due to viral or bacterial infection and preventing vascular leakage due to certain anticancer drugs or other anticancer therapies.SOLUTION: For example, 4-{(S)-2-[(S)-2-(methoxycarbonylamino)-3-phenylpropanamido]-2-[2-(thiophen-2-yl)thiazol-4-yl]ethyl}phenylsulfamic acid ammonium salt is administered as a compound that inhibits the intracellular catalytic site of a protein tyrosine phosphatase beta (PTP-&bgr;) molecule.