发明名称 |
DIAGNOSTIC METHOD AND THERAPEUTIC METHOD FOR PRE-ECLAMPSIA OR ECLAMPSIA |
摘要 |
PROBLEM TO BE SOLVED: To provide a method for therapy/prevention or diagnosis of pre-eclampsia or eclampsia in a subject.SOLUTION: A method for therapy or prevention of pre-eclampsia or eclampsia in a subject comprises a step of administering compound capable of binding to a soluble Flt-1 receptor (sFlt-1) to the subject, the administration having enough time and amount for therapy or prevention of pre-eclampsia or eclampsia in the subject. The method is further a method for diagnosis of a subject as having pre-eclampsia or eclampsia or as having a tendency of expressing the same, which comprises measuring the polypeptide level of sFlt-1, VEGF, or PlGF in a sample obtained from the subject. |
申请公布号 |
JP2014193920(A) |
申请公布日期 |
2014.10.09 |
申请号 |
JP20140119588 |
申请日期 |
2014.06.10 |
申请人 |
BETH ISRAEL DEACONNESS MEDICAL CENTER |
发明人 |
S ANANTH KARUMANCHI;MAYNARD SHARON;VIKAS P SUKHATME |
分类号 |
A61K45/00;A61B10/00;A61K31/4422;A61K31/465;A61K31/506;A61K31/522;A61K31/7076;A61K31/7088;A61K31/713;A61K38/00;A61K38/18;A61K38/19;A61K38/22;A61K39/395;A61K48/00;A61P15/00;A61P15/08;A61P25/08;C07K14/475;C07K14/485;C07K14/71;C07K16/12;C07K16/22;C07K16/28;C12N15/02;C12N15/09;C12N15/113;C12P21/08;C12Q1/02;C12Q1/48;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;G01N33/566;G01N33/68;G01N33/74 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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