发明名称 MRI-VISIBLE HYDROPHOBIC COPOLYMER
摘要 The invention relates to a hydrophobic thermoplastic copolymer which is in particular of use for manufacturing and/or coating medical devices, in particular implantable medical devices, characterized in that it is obtained by copolymerization, and in that it comprises at least one first monomer unit and at least one second monomer unit onto which is grafted a paramagnetic-ion-chelating ligand which can complex with such a paramagnetic ion or a paramagnetic-ion-chelating ligand which is complexed with such a paramagnetic ion, wherein the second monomer unit is grafted in sufficient amount for the copolymer to be visible in magnetic resonance imaging when it is complexed with said paramagnetic ion. The invention also relates to a method for obtaining said hydrophobic thermoplastic copolymer.
申请公布号 US2014302324(A1) 申请公布日期 2014.10.09
申请号 US201214364007 申请日期 2012.12.07
申请人 Centre National de la Recherche Scientifique 发明人 Coudane Jean;Darcos Vincent;El Habnouni Sarah;Garric Xavier;Lemaire Laurent;Nottelet Benjamin
分类号 A61K49/12 主分类号 A61K49/12
代理机构 代理人
主权项 1. A hydrophobic thermoplastic copolymer, comprising: a first monomer unit, and a second monomer unit on which is grafted a paramagnetic-ion-chelating ligand that optionally complexes with a paramagnetic ion or a paramagnetic-ion-chelating ligand complexed with the paramagnetic ion, wherein the second monomer unit is grafted in sufficient amount for the copolymer to be visible in magnetic resonance imaging when the second monomer unit is complexed with the paramagnetic ion.
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