发明名称 |
Recombinant Phage and Bacterial Detection Methods |
摘要 |
Methods of detecting target bacteria are provided. In some embodiments the methods comprise exposing the sample to a phage capable of infecting a set of target bacteria and comprising a heterologous nucleic acid sequence encoding a marker. In some embodiments the target bacteria comprise Listeria. In some embodiments the target bacteria are all Listeria. Recombinant Listeria phage comprising a heterologous nucleic acid sequence encoding a marker are also provided as are useful combinations of such phage and articles of manufacture comprising such phage, among other things. |
申请公布号 |
US2014302487(A1) |
申请公布日期 |
2014.10.09 |
申请号 |
US201414226889 |
申请日期 |
2014.03.27 |
申请人 |
Sample6 Technologies, Inc. |
发明人 |
Koeris Michael Sandor;Shivers Robert Patrick;Brownell Daniel Robert;Holder Jason Wyatt;Bowers Jayson Linn |
分类号 |
C12Q1/04 |
主分类号 |
C12Q1/04 |
代理机构 |
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代理人 |
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主权项 |
1. A method of detecting target bacteria, comprising:
providing a sample; exposing the sample to a first type of phage capable of infecting a first set of target bacteria and comprising a heterologous nucleic acid sequence encoding a first marker; exposing the sample to a second type of phage capable of infecting a second set of target bacteria and comprising a heterologous nucleic acid sequence encoding a second marker; and assaying for the presence of the first marker and the second marker in the exposed sample. |
地址 |
Boston MA US |