发明名称 METHODS AND COMPOSITIONS USING 4-AMINO-2-(2,6-DIOXO-PIPERIDINE-3-YL)-ISOINDOLINE-1,3-DIONE FOR TREATMENT AND MANAGEMENT OF CENTRAL NERVOUS SYSTEM CANCERS
摘要 Methods and compositions for treating, preventing or managing central nervous system cancers are disclosed. The methods encompass the administration of 4-amino-2- (2,6-dioxo-piperidine-3-yl)-isoindoline-l,3-dione, also known as Pomalidomide. Furthermore, provided herein are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods provided herein are also disclosed.
申请公布号 WO2014165482(A1) 申请公布日期 2014.10.09
申请号 WO2014US32483 申请日期 2014.04.01
申请人 CELGENE CORPORATION 发明人 TUN, HAN, W.
分类号 A61K31/454;A61K31/573;A61K39/395;A61K45/06;A61P35/00 主分类号 A61K31/454
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