发明名称 |
METHOD OF TREATING MUCUS HYPERSECRETION |
摘要 |
The present invention relates generally to a method of reducing unwanted airway tissue mucus secretion in a mammal and to agents useful for same. More particularly, the present invention relates to a method of reducing airway tissue mucus hypersecretion in a mammal by downregulating the functional level of activin or upregulating the functional level of follistatin. The method of the present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by airway tissue mucus dysfunction, such as overproduction of mucus or decreased mucus clearance, and where a reduction in mucus secretion levels would thereby alleviate the condition. |
申请公布号 |
US2014303068(A1) |
申请公布日期 |
2014.10.09 |
申请号 |
US201214354403 |
申请日期 |
2012.10.26 |
申请人 |
PARANTA BIOSCIENCES LIMITED |
发明人 |
O'Hehir Robyn;Hardy Charles;Kretser David De |
分类号 |
A61K38/17 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
1. A method of reducing airway tissue mucus secretion in a mammal, said method comprising downregulating the functional level of activin or upregulating the functional level of follistatin in said mammal. |
地址 |
Southbank AU |