发明名称 |
DRUG CONTAINING CARRIER INTO CELL FOR FORMING IMMUNE COMPLEX |
摘要 |
<p>The present inventors discovered that by forming a large immune complex comprising antigens containing two or more antigenic binding units (epitopes) and two or more antigen-binding molecules (for example, antibodies), elimination from the plasma of the antigens containing two or more antigenic binding units can be accelerated. Moreover, they found that by using this characteristic and by further using antigen-binding molecules having an ion-dependent antigen-binding activity, elimination of the antigens can further be accelerated and the above problem can be solved.</p> |
申请公布号 |
EP2787081(A1) |
申请公布日期 |
2014.10.08 |
申请号 |
EP20120853986 |
申请日期 |
2012.11.30 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
IGAWA, TOMOYUKI;HIRONIWA, NAOKA |
分类号 |
C07K16/28;A61K39/395;A61K45/00 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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