发明名称 NOVEL PEPTIDASE SUBSTRATES
摘要 The present invention relates to the use of a compound of the following formula (I), as an enzyme substrate for the detection of a peptidase activity or as a pH indicator: according to which: Y1 is a peptide, H or an alkyl; W1, W2, W3 and W4 are independently H, Br, Cl, F, I, alkyl, alkoxy, thiomethyl, perfluoroalkyl, nitro, cyano, carboxyl (including the esters or amides thereof) or any combination thereof; n=0, 1 or 2; U is N or N+R and V is CZ6N or N+R or else V is N or N+R and U is CZ6; R is H, alkyl, aralkyl, aryl, alkanoyl or alkylsulfonyl; Z1, Z2, Z3, Z4 and Z5 are independently H, Br, Cl, F, I, alkyl, aryl, alkoxy, perfluoroalkyl, nitro, cyano, carboxyl, sulfonyl, including the carboxyl or sulfonyl esters or amides, and salts thereof.
申请公布号 EP2459734(B1) 申请公布日期 2014.10.08
申请号 EP20100752884 申请日期 2010.07.28
申请人 BIOMÉRIEUX 发明人 FABREGA, OLIVIER;JAMES, ARTHUR;ORENGA, SYLVAIN;PERRY, JOHN;SALWATURA, VINDHYA LAKSHIKA;STANFORTH, STEPHEN
分类号 C12Q1/04;C12Q1/37;G01N33/84 主分类号 C12Q1/04
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