摘要 |
<p>The present invention provides an eperisone pharmaceutical composition with enhanced storage and pH stability which comprises: 20-60 wt% of eperisone or a pharmaceutically acceptable salt thereof; 1-30 wt% of at least one acidifier selected from D-glucaric acid, D-glucoascorbic acid, gluconic acid, D-glucuronic acid, gluconolactone, glucuronolactone, glutamic acid, itaconic acid, caffeic acid, glycyrrhizinate, ethanesulfonic acid, benzene sulfonic acid, dehydroascorbate, salicylic acid, salicylic sulfonic acid, gallic acid, nicotinic acid, or chlorogenic acid; 0.3-8 wt% of binder; and 10-80 wt% of diluent.</p> |