发明名称 |
PURINONE DERIVATIVE HYDROCHLORIDE |
摘要 |
A hydrochloride of 6-amino-9-[(3R)-1-(2-butynoyl)-3-pyrrolidinyl]-7-(4- phenoxyphenyl)-7,9-dihydro-8H-purin-8-one, which is a purinone derivative, is a compound having a Btk-selective inhibitory activity and excellent metabolism stability, capable of solubilizing and absorbing a free base satisfactorily, and capable of being crystallized. Therefore, the compound can be used as a therapeutic agent for diseases associated with a B cell or a mast cell. |
申请公布号 |
PH12014501503(A1) |
申请公布日期 |
2014.10.08 |
申请号 |
PH2003120145015 |
申请日期 |
2014.06.27 |
申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
YAMAMOTO, SHINGO;YOSHIZAWA, TOSHIO |
分类号 |
A61P35/00;A61P35/02;A61P37/02;A61P37/08;A61P43/00;C07D473/34 |
主分类号 |
A61P35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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