Mucosal formulation

摘要

Provided, among other things, is a method of treating or ameliorating an indication of mucosal or adjacent tissue comprising periodically applying to mucosa at or adjacent to disease affected tissue a rinse comprising: an effective amount of appropriate composition of herbal bioactive comprising active(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea; an antimicrobially effective amount of a quaternary ammonium surfactant; and optionally a polymer or mixture of polymers effective to coat said tissue and entrap said extract(s).

主权项

1. A method of treating or ameliorating an indication of anal or vaginal mucosal tissue comprising periodically applying to anal or vaginal mucosa at or adjacent to disease affected tissue a formulation comprising
an antiinflammatory effective amount of herbal extracts including Sambucus nigra, Centella asiatica and Echinacea purpurea defining a weight amount of plant extract solids in the formulation, wherein Sambucus nigra extract is more than 50% to 90% by weight of the plant extract solids and Centella asiatica is 1% to less than 50% by weight of the plant extract solids, a plasticizer in an amount from 10 to 45% by weight of the formulation, and an antimicrobially effective amount of a surfactant that is a 1-alkylpyridinium salt, where alkyl is C8-C36, the surfactant present in an amount from 0.01 to 2% of the formulation by weight.