Treating allergic airway disorders using anti-IL-20 receptor antibodies

摘要

Treatment of an allergic airway disorder (e.g., asthma or bronchial airway obstruction) using anti-IL-20R1 antibodies such as mAb51D, mAb7GW, or functional variants thereof.

主权项

1. A method for treating an allergic airway disorder, comprising administering to a subject in need thereof an effective amount of an anti-interleukin-20 receptor subunit 1 (anti-IL-20R1) antibody, wherein the anti-IL-20R1 antibody comprises:
a heavy chain variable region (VH) that includes a VH CDR1, a VH CDR2, and a VH CDR3 which are identical to the corresponding VH CDRs of mAb51D or mAb7GW, and a light chain variable region (VL) that includes a VL CDR1, a VL CDR2, and a VL CDR3 which are identical to the corresponding VL CDRs of mAb51D or mAb7GW.