| 发明名称 | Glycopegylation methods and proteins/peptides produced by the methods | ||
| 摘要 | The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide. | ||
| 申请公布号 | US8853161(B2) | 申请公布日期 | 2014.10.07 |
| 申请号 | US201113246512 | 申请日期 | 2011.09.27 |
| 申请人 | Novo Nordisk A/S | 发明人 | DeFrees Shawn;Zopf David A.;Bayer Robert J.;Hakes David James;Bowe Caryn;Chen Xi |
| 分类号 | A61K38/00;A61P7/00 | 主分类号 | A61K38/00 |
| 代理机构 | Leydig, Voit & Mayer, Ltd. | 代理人 | Leydig, Voit & Mayer, Ltd. |
| 主权项 | 1. A covalent conjugate between Factor IX and a water-soluble polymer selected from the group consisting of poly(ethers), poly(amines), and poly(carboxylic acids), wherein said water-soluble polymer is covalently attached to Factor IX through an intact glycosyl linking group. | ||
| 地址 | Bagsvaerd DK | ||