Method of fabricating microfluidic systems

摘要

A method of fabricating a microfluidic system having microfluidic channels on a surface of a hydrophilic substrate, the method including the steps of: hydrophobizing the substrate surface; locating a mask defining the substrate surface, the mask having open areas defining the periphery of the microfluidic channels; and applying an irradiation treatment to areas of the substrate surface exposed by the open areas of the mask, said exposed areas becoming hydrophilic to therefore form said microfluidic channels.

主权项

1. A method of fabricating a flexible microfluidic device having microfluidic channels on a surface of a flexible hydrophilic substrate formed of cellulosic material, the method including the steps of:
(a) hydrophobizing the flexible hydrophilic substrate surface by absorbing or adsorbing a hydrophobic substance on or within the substrate; (b) locating a mask defining the substrate surface, the mask having open areas defining the periphery of the microfluidic channels; and (c) applying an irradiation treatment to areas of the substrate surface exposed by the open areas of the mask, said exposed areas becoming hydrophilic to therefore form said microfluidic channels while retaining flexibility of the flexible hydrophilic substrate.