METHOD FOR PRODUCING NANOBUBBLE LIQUID OF ORGAN PRESERVATION

摘要

The present invention relates to a manufacturing method for a nanobubble mixed organ preserving solution comprising: (a) a step of mixing sodium chloride with ultrapure water obtained by purifying raw water through a filtering process of three steps of an ultrafilter, an ion filter and electrodeionization (EDI); (b) a step of generating nanobubbles in high pressure conditions by applying oxygen to a mixed solution; (c) a step of manufacturing nanobubble mixed base water by removing ionic materials and sodium ions by passing a nanobubble mixed solution through an ultrafilter and an ion filter; (d) a step of mixing an raw organ preserving material and the base water manufactured in step (c); (e) a step of adding the base water manufactured in step (c) to a mixture of step (d); and (f) a step of mixing nanobubbles in high pressure conditions by applying oxygen and carbon dioxide to a mixed solution of step (e), and to a manufacturing apparatus for a nanobubble mixed organ preserving solution. The manufacturing apparatus for an organ preserving solution according to the present invention facilitates process working since a manufacturing process and apparatus washing are performed at the same time by installing a clean-in-place (CIP) device. An organ preserving solution manufactured by the manufacturing process is useful in medical industry fields by eminently increasing the effects of compositions with ischemia-reperfusion preventing effects clinically used in the conservation of a transplantable organ by nanobubbles.