发明名称 |
18-METHYL-19-NOR-ANDROST-4-EN-17,17-SPIROETHER (18-METHYL-19-NOR-20-SPIROX-4-EN-3-ONE), AND PHARMACEUTICAL PRODUCTS COMPRISING THE SAME |
摘要 |
The invention relates to novel 18-methyl-19-nor-androst-4-en-17,17- spiroether of general formula (I), where Z = O, two H, =NOR or =NNHSO2R, R = H, or straight or branched chain C1-4 or C3-4alkyl, R4 = H, halogen, or CF3 and R6 and/or R7 are .alpha.- or ß-positioned and R6 and R7 independently = H or straight or branched chain C1-4 or C3-4alkyl or a straight or branched chain C2-4 or C3-4alkylene or a saturated C3-5 cycloalkyl, or together form a methylene group or a double bond. The novel compounds have gestagenic and antimineralcorticoid action. |
申请公布号 |
CA2656443(C) |
申请公布日期 |
2014.10.07 |
申请号 |
CA20072656443 |
申请日期 |
2007.06.29 |
申请人 |
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT |
发明人 |
BOHLMANN, ROLF;KUHNKE, JOACHIM;HUEBNER, JAN;GALLUS, NORBERT;MENGES, FREDERIK;BORDEN, STEFFEN;MUHN, HANS-PETER;PRELLE, KATJA |
分类号 |
C07J53/00;A61K31/58;A61P5/34;A61P5/42 |
主分类号 |
C07J53/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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