摘要 |
<p>PROBLEM TO BE SOLVED: To provide a novel pyrimidine nucleoside compound exhibiting more excellent balance of antitumor effect and toxicity than that of existing pyrimidine nucleoside compounds.SOLUTION: The compound is represented by the general formula (1): [in the formula, one of A1 and A2 is a hydrogen atom or a group represented by (R1)(R2)(R3)Si- and the other is a group represented by (R4)(R5)(R6)Si-, or A1 and A2 are taken together to form a cyclic group represented by -(R7)(R8)Si- or -(R9)(R10)Si-O-Si(R11)(R12)-; R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 each represents an alkyl group having a carbon number of 1 to 12 which may have a substituent group or an aryl group having a carbon number of 6 to 14 which may have a substituent group].</p> |