| 发明名称 |
Proteina de fusion que comprende una variante de fgf21 y una region fc. |
| 摘要 |
The invention relates to the identification of fusion proteins comprising polypeptide and protein variants of fibroblast growth factor 21 (FGF21) with improved pharmaceutical properties. Also disclosed are methods for treating FGF21-associated disorders, including metabolic conditions. |
| 申请公布号 |
CL2014000736(A1) |
申请公布日期 |
2014.10.03 |
| 申请号 |
CL20140000736 |
申请日期 |
2014.03.25 |
| 申请人 |
NOVARTIS AG |
发明人 |
BRIAN R. BOETTCHER;DOUGLAS S. DANIELS;NORIO HAMAMATSU;STUART LICHT;STEPHEN CRAIG WELDON;SHARI, L. CAPLAN |
| 分类号 |
C07K14/50;A61K38/18;A61K47/48;C07K16/46 |
主分类号 |
C07K14/50 |
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