摘要 |
The invention relates to iRNA, e.g., double-stranded ribonucleic acid (dsRNA), compositions targeting the complement component C5 gene, and methods of using such iRNA, e.g., dsRNA, compositions to inhibit expression of C5 and to treat subjects having a complement component C5-associated disease, e.g., paroxysmal nocturnal hemoglobinuria. |
申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
FITZGERALD, KEVIN;BUTLER, JAMES;BETTENCOURT, BRIAN;BORODOVSKY, ANNA;KUCHIMANCHI, SATYANARAYANA;CHARISSE, KLAUS;MANOHARAN, MUTHIAH;MAIER, MARTIN;RAJEEV, KALLANTHOTTATHIL, G.;FOSTER, DONALD |