发明名称 FLUORENE COMPOUND AND PHARMACEUTICAL USE THEREOF
摘要 <p>PROBLEM TO BE SOLVED: To provide preventive or therapeutic agents for diabetes, diabetic complication, diabetic microangiopathy complication, insulin resistance syndrome, metabolic syndrome, hyperglycemia, hyperlipidemia, atherosclerotic sclerosis, failure, cardiomyopathy, myocardial ischemia, cerebral ischemia, stroke, pulmonary hypertension, hyperlactacidemia, mitochondrial diseases, mitochondrial encephalomyopathy or cancer, i.e. PDHK inhibitors and the like.SOLUTION: There are provided compounds represented by the general formula [I] or pharmaceutically acceptable salts thereof or solvates thereof. [I], where each symbols are as described in the specification.</p>
申请公布号 JP2014185159(A) 申请公布日期 2014.10.02
申请号 JP20140105236 申请日期 2014.05.21
申请人 JAPAN TOBACCO INC 发明人 MOTOMURA TAKANAO;NAGAMORI HIROMASA;SUZAWA KOICHI;ITO HIROTSUGU;MORITA TORU;KOBAYASHI AKIRA;SHINKAI HISASHI
分类号 C07D231/12;A61K31/415;A61P3/10;A61P9/00;A61P19/06;A61P35/00 主分类号 C07D231/12
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