发明名称 |
PHARMACEUTICAL COMPOSITION FOR ELIMINATION OF CANCER STEM CELLS |
摘要 |
The preset invention relates to use of antipsychotic phenothiazine derivative for eliminating cancer stem cells (CSCs) and/or preventing a cancer. The invention also provides a pharmaceutical composition for treating a cancer, and/or preventing or delaying cancer recurrence comprising trifluoperazine and an anti-cancer drug, such as gefitinib or cisplatin. |
申请公布号 |
US2014294994(A1) |
申请公布日期 |
2014.10.02 |
申请号 |
US201214354873 |
申请日期 |
2012.10.29 |
申请人 |
Huang Ch-Ying |
发明人 |
Huang Ch-Ying |
分类号 |
A61K31/5415;A61N5/10;A61K45/06 |
主分类号 |
A61K31/5415 |
代理机构 |
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代理人 |
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主权项 |
1. Use of a compound having the structure of formula I in the manufacture of a medicament for eliminating cancer stem cells (CSCs):wherein A is N(CH3)2, a N-methyl or N-ethyl piperazinyl group, a N-(hydroxyethyl)piperazinyl group, or a N-methyl piperidinyl group, and B is SCH3, Cl, CF3, or H. |
地址 |
Taipei City TW |