Method and formulation for inhalation

摘要

This invention relates to drug delivery and in particular to the delivery of biologically active agents in the form of dry powders for inhalation. The invention also relates to methods for preparing such dry powder formulations and methods for their use.

主权项

1. A method for preparing a dry powder for inhalation comprising:
preparing an aqueous solution and/or suspension comprising a biologically active protein or peptide, one or more mono, di- or polysaccharides and/or amino acids capable of forming an amorphous glass matrix, and L-leucine; and spray drying the aqueous solution or suspension to produce a dry powder suitable for inhalation.