发明名称 SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF CARDIOVASCULAR DISORDERS
摘要 The invention relates to substituted oxopyridine derivatives of the formula in which R1 is a group of the formula, where * is the attachment site to the oxopyridine ring, R6 is bromine, chlorine, fluorine, methyl, difluoromethyl, trifluoromethyl, methoxy, difluoromethoxy or trifluoromethoxy, R7 is bromine, chlorine, fluorine, cyano, nitro, hydroxyl, methyl, difluoromethyl, trifluoromethyl, methoxy, ethoxy, difluoromethoxy, trifluoromethoxy, ethynyl, 3,3,3-trifluoroprop-l-yn-l-yl or cyclopropyl, and to processes for preparation thereof and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular diseases, preferably thrombotic or thromboembolic diseases and of oedemas, and also of ophthalmological disorders.
申请公布号 CA2908085(A1) 申请公布日期 2014.10.02
申请号 CA20142908085 申请日期 2014.03.27
申请人 BAYER PHARMA AKTIENGESELLSCHAFT 发明人 ROHRIG, SUSANNE;HILLISCH, ALEXANDER;STRASBURGER, JULIA;HEITMEIER, STEFAN;SCHMIDT, MARTINA VICTORIA;SCHLEMMER, KARL-HEINZ;TERSTEEGEN, ADRIAN;BUCHMULLER, ANJA;GERDES, CHRISTOPH;SCHAFER, MARTINA;KINZEL, TOM;TELLER, HENRIK;SCHIROK, HARTMUT;KLAR, JURGEN;JIMENEZ NUNEZ, ELOISA
分类号 C07D413/14;A61K31/4412;A61K31/4418;A61K31/4427;A61P7/00;A61P9/00;C07D213/64;C07D213/69;C07D213/85;C07D401/12;C07D405/06;C07D409/06;C07D413/12;C07D417/12 主分类号 C07D413/14
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