发明名称 |
BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS |
摘要 |
<p>This application relates to chemical compounds which may act as inhibitors of, or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula (I) wherein R1a, R1b, R2a, R2b, R3, and X are described herein.</p> |
申请公布号 |
CA2907502(A1) |
申请公布日期 |
2014.10.02 |
申请号 |
CA20142907502 |
申请日期 |
2014.03.27 |
申请人 |
GILEAD SCIENCES, INC. |
发明人 |
AKTOUDIANAKIS, EVANGELOS;CHIN, GREGORY;CORKEY, BRITTON KENNETH;DU, JINFA;ELBEL, KRISTYNA;JIANG, ROBERT H.;KOBAYASHI, TETSUYA;MARTINEZ, RUBEN;METOBO, SAMUEL E.;MISH, MICHAEL;SHEVICK, SOPHIE;SPERANDIO, DAVID;YANG, HAI;ZABLOCKI, JEFF |
分类号 |
C07D413/14;A61K31/42;A61P35/00;C07D413/04;C07D417/14 |
主分类号 |
C07D413/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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