| 摘要 |
Provided is a hydrophilic polymer derivative having a benzylidene acetal linker, of which the hydrolysis rate at a pH value of a weakly acidic environment in a living body can be controlled accurately. A hydrophilic polymer derivative having a benzylidene acetal linker, which is represented by formula (1) (wherein R1 represents a hydrogen atom or a hydrocarbon group; R2, R3, R4, R5 and R6 independently represent a hydrogen atom or a substituent, wherein at least one of R3, R4 and R5 represents an electron-withdrawing substituent or R2 and/or R6 represents a substituent; X1 represents a chemically reactive functional group; P represents a hydrophilic polymer; w represents an integer of 1 to 8; and Z1 and Z2 independently represent a selected bivalent spacer). |
