发明名称 |
ANTI-CD276 POLYPEPTIDES, PROTEINS, AND CHIMERIC ANTIGEN RECEPTORS |
摘要 |
Polypeptides and proteins that specifically bind to and immunologically recognize CD276 are disclosed. Chimeric antigen receptors (CARs), anti-CD276 binding moieties, nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the polypeptides and proteins are also disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed. |
申请公布号 |
WO2014160627(A1) |
申请公布日期 |
2014.10.02 |
申请号 |
WO2014US31543 |
申请日期 |
2014.03.24 |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;BIOMED VALLEY DISCOVERIES, INC. |
发明人 |
ORENTAS, RIMAS J.;ZHU, ZHONGYU;MACKALL, CRYSTAL L.;DIMITROV, DIMITER S.;ST. CROIX, BRADLEY;SAHA, SAURABH |
分类号 |
C07K14/705;C07K16/28 |
主分类号 |
C07K14/705 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|