发明名称 |
NON-REPLICATIVE TRANSDUCTION PARTICLES AND TRANSDUCTION PARTICLE-BASED REPORTER SYSTEMS |
摘要 |
Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non- replicative transduction particles as reporter molecules. |
申请公布号 |
CA2905341(A1) |
申请公布日期 |
2014.10.02 |
申请号 |
CA20142905341 |
申请日期 |
2014.03.13 |
申请人 |
GENEWEAVE BIOSCIENCES, INC. |
发明人 |
REY, DIEGO ARIEL;DEFOREST, NIKOL;COX, HEATHER;SHUKLA, SONI |
分类号 |
A61K35/76;C12N7/01;C12N15/74 |
主分类号 |
A61K35/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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