发明名称 |
Lipid-derived neutral nanoparticles |
摘要 |
Disclosed herein are novel lipids and liposomal compositions prepared using such compounds and related methods of neutralizing or otherwise modifying such liposomal compositions. The lipids described herein are useful for example, as liposomal vehicles to facilitate the delivery of encapsulated polynucleotides to target cells and the subsequent transfection of such target cells. In certain embodiments, one or more of the compounds that comprise the liposomal delivery vehicle may be neutralized or further modified such that the properties of the liposomal delivery vehicle are modified. |
申请公布号 |
AU2013237874(A1) |
申请公布日期 |
2014.10.02 |
申请号 |
AU20130237874 |
申请日期 |
2013.03.29 |
申请人 |
SHIRE HUMAN GENETIC THERAPIES, INC. |
发明人 |
DEROSA, FRANK;GUILD, BRAYDON CHARLES;HEARTLEIN, MICHAEL |
分类号 |
A61K9/127;C12N15/11;C12N15/88;G01N33/92 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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