METHODS FOR USING LUBIPROSTONE TO ABSORB FLUID FROM THE SUBRETINAL SPACE

摘要

Particular aspects of the invention provide methods for decreasing the amount of fluid present in the subretinal space of the eye by administering a prostone to the basolateral side of the retinal pigment epithelium. Adverse ocular conditions associated with the accumulation of fluid in the subretinal space (like age-related macular degeneration, chronic macular edema, diabetic retinopathy, retinal detachment, glaucoma, uveitis) can be treated by administering an amount of a prostone (preferably lubiprostone, unoprostone, cobiprostone) to the basolateral side of the retinal pigment epithelium effective to remove excess fluid from the subretinal space.