发明名称 |
MEASUREMENT OF FGF21 AS A BIOMARKER OF FRUCTOSE METABOLISM AND METABOLIC DISEASE |
摘要 |
The invention provides, inter alia, methods of monitoring the fructose response of a subject by determining the level of fibroblast growth factor 21 (FGF21) gene expression product in a biological sample (such as a serum sample) from the subject, where the subject was previously administered a fructose bolus. The invention also provides methods of monitoring the response of a subject to a treatment for a disorder of metabolism, for discriminating fructose intolerance from other gastrointestinal disorders not associated with fructose intolerance, for identifying a subject at risk for developing a disorder of metabolism, as well as methods of treatment for a disorder of metabolism. |
申请公布号 |
WO2014159961(A1) |
申请公布日期 |
2014.10.02 |
申请号 |
WO2014US25527 |
申请日期 |
2014.03.13 |
申请人 |
BETH ISRAEL DEACONESS MEDICAL CENTER, INC. |
发明人 |
MARATOS-FLIER, ELEFTHERIA;HERMAN, MARK;DUSHAY, JODY;FISHER, FFOLLIOTT MARTIN |
分类号 |
G01N33/68;G01N33/74 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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