Tiacumicin Production

摘要

Methods, processes and materials for the production and recovery of Tiacumicins produced by culturing a microorganism belonging to the species Dactylosporangium aurantiacum subspecies hamdenensis having the ability to produce and accumulate one or more Tiacumicin in a nutrient medium comprising a carbon source, a nitrogen source, trace elements such as inorganic salts, and an adsorbent, wherein said nitrogen source comprises fish powder, and wherein said Tiacumicin is produced in a yield greater than about 50 mg/L broth.

主权项

1. A process of producing Tiacumicin B that comprises culturing a microorganism having the ability to produce Tiacumicin B in a nutrient medium and accumulating at least one Tiacumicin B in the nutrient medium, wherein the yield of at least one Tiacumicin B is greater than about 50 mg/L of whole fermentation broth.