发明名称 |
ISOLATION OF FACTOR H FROM FRACTION I PASTE |
摘要 |
Among other aspects, the present disclosure provides methods for preparing enriched compositions of plasma-derived Factor H from fractions formed during the manufacturing processes of established plasma-derived therapeutic compositions. Specifically, methods are provided for the isolation of Factor H from Fraction precipitates commonly discarded during the manufacture of commercial IgG therapeutics. Advantageously, the Factor H compositions prepared according to these methods have improved proteolytic profiles and reduced amidolytic activity. |
申请公布号 |
AU2013203048(A1) |
申请公布日期 |
2014.10.02 |
申请号 |
AU20130203048 |
申请日期 |
2013.04.09 |
申请人 |
BAXTER HEALTHCARE S.A.;BAXTER INTERNATIONAL INC. |
发明人 |
BAIRSTOW, SHAWN F.;RAMACHANDRAN, SINDHU;JOHNSON, RICHARD;SCHILL, NICHOLAS J. |
分类号 |
C07K1/14;A61K31/00;C07K14/435 |
主分类号 |
C07K1/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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