| 发明名称 |
PROCESS FOR RECOVERY OF NALMEFENE HYDROCHLORIDE |
| 摘要 |
The present invention relates to an improved process for recovery of nalmefene hydrochloride [17-(cyclopropylmethyl)-4,5- alpha-epoxy-6-methylenemorphinan-3,14-diol hydrochloride] from an aqueous composition containing nalmefene and certain impurities. |
| 申请公布号 |
US2014296525(A1) |
申请公布日期 |
2014.10.02 |
| 申请号 |
US201214294707 |
申请日期 |
2012.12.06 |
| 申请人 |
H. Lundbeck A/S |
发明人 |
De Faveri Carla;Stivanello Mariano |
| 分类号 |
C07D489/08 |
主分类号 |
C07D489/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process for recovery of nalmefene hydrochloride from an aqueous composition containing nalmefene hydrochloride and naltrexone, said process comprising the step of isolating nalmefene hydrochloride from an aqueous suspension comprising naltrexone bisulfite adduct and solid nalmefene hydrochloride. |
| 地址 |
Valby DK |
