发明名称 |
METHODS FOR PREDICTING RISK OF METASTASIS IN CUTANEOUS MELANOMA |
摘要 |
The invention as disclosed herein in encompasses a method for predicting the risk of metastasis of a primary cutaneous melanoma tumor, the method encompassing measuring the gene-expression levels of at least eight genes selected from a specific gene set in a sample taken from the primary cutaneous melanoma tumor; determining a gene-expression profile signature from the gene expression levels of the at least eight genes; comparing the gene-expression profile to the gene-expression profile of a predictive training set; and providing an indication as to whether the primary cutaneous melanoma tumor is a certain class of metastasis or treatment risk when the gene expression profile indicates that expression levels of at least eight genes are altered in a predictive manner as compared to the gene expression profile of the predictive training set. |
申请公布号 |
CA2904283(A1) |
申请公布日期 |
2014.10.02 |
申请号 |
CA20142904283 |
申请日期 |
2014.02.28 |
申请人 |
CASTLE BIOSCIENCES, INC. |
发明人 |
COOK, ROBERT WILLIS;MAETZOLD, DEREK;OESCHLAGER, KRISTEN |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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